Veterinary medicine has advanced many folds in recent times. When it comes to protecting dogs against parasites like fleas and ticks, today there are several drugs available in the market that are far more efficient than there were a couple of decades ago. Sarolaner is one of the latest additions to this class. Ever since its introduction, this drug is extensively being used to protect animals against a diverse range of pests.
This blog exhibits all the necessary information you should know about this veterinary antiparasitic remedy. Read through to learn more of it.
Sarolaner – A Brief
Discovered and developed by Zoetis – a global animal healthcare product manufacturing company – and approved by the U.S. Food and Drug Administration, sarolaner is the third drug of the isoxazolines family after afoxolaner and fluranaer.
Sarolaner is a broad-spectrum ectoparasiticide, meaning that it kills a variety of external parasites living on animals’ body surfaces, such as fleas and ticks for one month.
Sarolaner – Mode of Action
Once given to dogs, this drug works systematically and kills parasites from the treated animal’s body. It works by causing overstimulation in the arthropod nervous system of parasites.
After administration, sarolaner quickly gets distributed throughout dog’s body and is rapidly absorbed into their blood. As soon as parasites (fleas and ticks) take the blood meal from sarolaner-treated animals, they ingest sarolaner and die.
Sarolaner – Parasites Covered
Sarolaner provides protection against parasites that live externally of its host including,
- fleas
- lone star ticks
- Gulf coast ticks
- American dog ticks
- black-legged ticks
- brown dog ticks
Sarolaner – Efficacy
Sarolaner is one of the fastest-acting components. This drug starts killing fleas within 3-4 hours after administration and kills more than 90% of fleas within 24 hours following the treatment. It is known to achieve more than 90% effectiveness against ticks 48 hours after administration.
Sarolaner – Precautions
- Sarolaner belongs to the isoxazoline group of drugs. This group has been associated with neurologic adverse reactions, such as seizures, ataxia and tremors.
- It is recommended to use it with caution in dogs with a history of seizures or other neurologic disorders.
- The safe use of sarolaner has not been evaluated in pregnant, breeding and lactating dogs.
Sarolaner – Brands
Zoetis, the inventor of sarolaner has introduced a couple of brands with sarolaner as their primary ingredient, i.e. Simparica and Simparica Trio. Formulated for dogs, both these products protect against a range of parasites. Here’s a short summary:
Simparica Chewable
Sarolaner
Made in a tasty flavored chew, Simparica for dogs is a monthly flea and tick treatment for 6 months and older puppies and dogs, weighing 2.8 lbs or more.
Composition:
The minimum recommended dosage of Simparica (sarolaner) is 0.91 mg/lb (2 mg/kg). Take a look at pack-by-pack composition.
Administration:
- Give one chew per month.
- It can be given directly for chewing or mixed in the dog food.
Offered Protection:
- Kills adult fleas
- Treats and prevents flea infestations
- Treats and controls lone star tick, Gulf coast tick, American dog tick, black-legged tick and brown dog tick infestations
- Indicated for the prevention of Lyme disease
Simparica Trio
Sarolaner, Moxidectin, Pyrantel
Simparica Trio is a palatable monthly broad-spectrum treatment for 8 weeks and older puppies and dogs, weighing 2.8 lbs or more.
Composition:
The minimum recommended dosage of Simparica Trio is 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 µg/kg) moxidectin and 2.27 mg/lb (5mg/kg) pyrantel (as pamoate salt).
Administration:
- Give one chew every month.
- It can be given with or without food.
Offered Protection:
- Prevents heartworm disease
- Treats and controls roundworms and hookworms
- Kills adult fleas
- Treats and prevents flea infestations
- Treats and controls lone star tick, Gulf coast tick, American dog tick, black-legged tick and brown dog tick infestations
- Recommended for the prevention of Lyme disease
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Summary
Introduced by Zoetis, Sarolaner is a highly efficient drug, belonging to the isoxazoline class that protects dogs against external parasites such as fleas and ticks for one month. Be cautious while using this component on your dogs if they have experienced seizures or other neurologic illnesses in the past. It would be wise to talk to a veterinarian before using sarolaner on your four-legged friends.
